My experience: I have been running Sjogren’s Syndrome (ETDF), Eyesight to Improve (XTRA), and Astigmatism (ETDF) since the beginning of February and have noticed improvement. At night my alarm clock used to be a red blur with no number being identifiable. Now I can make out the numbers. It’s not clear, but I can see what it says without squinting. My vision at the start was -2.00 and -3.25. I have severe astigmatisms. I don’t go to the eye doc again till next spring. But something is changing, because I can also read large print without my glasses as well, where as before I couldn’t.